Efficacy of Plerixafor for Peripheral Stem Cell Mobilisation in Autologous Transplantation: A Single Centre Study
نویسندگان
چکیده
منابع مشابه
Autologous stem cell transplantation as frontline strategy for peripheral T-cell lymphoma: A single-centre experience
Objective To determine the efficacy and prognosis of autologous hematopoietic stem cell transplantation (ASCT) as frontline treatment for peripheral T cell lymphoma (PTCL). Methods Clinical data from 46 PTCL patients who achieved complete (CR) or partial remission (PR) after ASCT from October 1996 to July 2014 were analysed retrospectively. Results Median patient age was 32 (range: 15-68) years...
متن کاملPlerixafor for Stem Cell mobilisation prior to BMT
The drug and the review Plerixafor was licensed in the UK in August 2009 to be used in combination with G-CSF to enhance mobilisation of haematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with lymphoma and multiple myeloma whose cells mobilise poorly. The recommended dose of plerixafor is 0.24mg/kg body weight per day (to a max...
متن کاملAutologous Peripheral Hematopoietic Stem Cell Transplantation
From ten patients with advanced malignant disease involving the bone marrow, autologous hematopoietic stem cells were collected from the peripheral blood during eight four-hour pheresis procedures and cryopreserved. No manipulations to increase the number of stem cells circulating in the blood were used during the collections. Following marrow ablative chemotherapy or chemoradiotherapy. the aut...
متن کاملHodgkin’s Lymphoma Occurring Secondary to Autologous Stem Cell Transplantation in Plasma Cell Leukemia; A Case Report
Survival of patients with multiple myeloma has improved substantially because of availability of new therapies including autotransplants, immunomodulating drugs and proteasome-inhibitors. Second primary cancers have emerged as an important determinant of morbidity and mortality among cancer survivors. Even though there is an increased risk of new cancers of the lymphoreticular and haematopoetic...
متن کاملAutologous stem cell transplantation for mantle cell lymphoma – single centre experience
AIM OF THE STUDY Mantle cell lymphoma (MCL) is a B-cell neoplasm showing resistance to conventional chemotherapy. High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) may result in higher progression-free (PFS) and overall survival (OS) when used as a consolidation for younger and fit patients. MATERIAL AND METHODS We retrospectively evaluated the results of ASCT for...
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ژورنال
عنوان ژورنال: Journal of Cancer Therapy
سال: 2020
ISSN: 2151-1934,2151-1942
DOI: 10.4236/jct.2020.118041